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Yessi Pratiwi — January 11, 2008 / 3:15 pm
Having a food allergy means that the immune system responds to a food protein as if it was harmful. There is currently no way to treat food allergy. The only way for sufferers to manage the problem is to avoid certain foods and make sure they have injectable adrenaline at hand.
Dr Claudio Nicoletti, the leading researcher at the Institute of Food Research in Norwich found that special types of white blood cells called dendritic cells are important in helping the immune system decide on how to respond to foreign molecules.
Then, in the latest research, Dr Nicoletti compared the activity of dendritic cells in the gut and in the spleen of allergic and allergy resistant mice. He found that in the gut of susceptible mice, dendritic cells have stopped producing IL-12. He found that a molecule called Interleukin-12 (IL-12) is absent during allergic responses. So, by delivering an allergen in the presence of IL-12, allergic reactions could be brought back under control, he suggests.
The research was supported by a grant from the Biotechnology and Biological Sciences Research Council and intramural funds of the University of Siena.
Adapted from materials provided by Institute of Food Research.
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