You're here: My Science Blogging » Discovery » Article: Cultured Blood-forming Stem Cells From Human Fat Tissue For Blood Cancer Therapy
Yessi Pratiwi — December 29, 2007 / 11:07 pm
It is widely known that adipose tissue has the ability to rapidly expand or contract in accordance with nutritional constraints.
Recently, using a cell-sorting method known as flow cytometry, the researchers at the University of Pittsburgh School of Medicine detected a broad spectrum of blood-forming, or hematopoietic, cells among the cultured cells at varying stages of differentiation.
They observed both early and mature red blood cells, and found that hematopoietic stem cells are an integral part of normal adipose tissue. They took cells from the stromal vascular fraction of normal adipose tissue and basically gave them bone marrow food to see what would happen. They were able to culture a variety of hematopoietic cells, including blood progenitor cells.
In other words, it can be said that they have successfully isolated and cultured human hematopoietic stem cells from fat, or adipose, tissue, suggesting that they have found another important source of cells for reconstituting the bone marrow of patients undergoing intensive radiation therapy for blood cancers.
Adapted from materials provided by University of Pittsburgh Schools of the Health Sciences.
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