You're here: My Science Blogging » Discovery » Article: Identification of Enzymes to Brainpower
Yessi Pratiwi — November 18, 2007 / 10:50 pm
Brain is the organ of the body that performs the function of memory. We can still improve and expand our mind, it doesn’t matter how brainy we are or how much education we’ve had.
Getting old doesn’t have to mean worsening memory, slower reactions and fuzzy thinking, because MIT researchers and colleagues are managed to find the enzymes that manipulate a key scaffolding protein for synapses, the connections through which brain cells communicate. Synapses are weakened and lost in neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease.
They identified a major underlying mechanism through which synapses are strengthened and maintained. The key building block of synapses is a protein called postsynaptic density-95 (PSD-95). The more PSD-95 molecules, the bigger and stronger the synapse.
The manipulation of PSD-95 through phosphorylation is believed could lead to bigger and more robust synapses, which would boost brainpower in both normal and diseased brains.
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